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https://scidar.kg.ac.rs/handle/123456789/20669
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Поље DC-а | Вредност | Језик |
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dc.contributor.author | Obradović, Ana | - |
dc.contributor.author | Vukić, Milena | - |
dc.contributor.author | Paunović, Milica | - |
dc.contributor.author | Ognjanović, Branka | - |
dc.contributor.author | Vukovic, Nenad | - |
dc.contributor.author | Kačániová, Miroslava | - |
dc.contributor.author | Matić, Miloš | - |
dc.date.accessioned | 2024-04-23T10:31:05Z | - |
dc.date.available | 2024-04-23T10:31:05Z | - |
dc.date.issued | 2024 | - |
dc.identifier.isbn | 9788687611917 | en_US |
dc.identifier.uri | https://scidar.kg.ac.rs/handle/123456789/20669 | - |
dc.description.abstract | The aim of this study was to investigate antitumor capacity of different Tanacetum balsamita essential oils by measuring apoptosis rate, MMP-9 concetration and Nrf-2 expression level in human MBA-MB-468 and MDA-MB-231 cells. The tested EOs expressed proapoptotic effects, significantly inhibited the MMP-9 concentration and down-regulated the expression level of Nrf-2. The obtained data suggest that the tested EOs exert considerable antitumor activity elevating apoptosis level and inhibiting the motility of tested cancer cells. The reduced levels of Nrf-2 expression suggest decreased defense potential for oxidative disturbances, which could be the major antitumor mechanism detected in the study. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Faculty of Agronomy in Čačak, University of Kragujevac | en_US |
dc.relation | This study was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Agreement No. 451-03-66/2024-03/200122 and Agreement No. 451-03-65/2024-03/200122). | en_US |
dc.relation.ispartof | 2nd INTERNATIONAL SYMPOSIUM ON BIOTECHNOLOGY | en_US |
dc.rights | CC0 1.0 Universal | * |
dc.rights.uri | http://creativecommons.org/publicdomain/zero/1.0/ | * |
dc.subject | Tanacetum balsamita essential oils | en_US |
dc.subject | breast cancer cell lines | en_US |
dc.subject | breast cancer cell lines | en_US |
dc.subject | Nrf-2 | en_US |
dc.subject | MMP-9 | en_US |
dc.subject | apoptosis rate | en_US |
dc.title | ANTITUMOR EFFECTS OF TANACETUM BALSAMITA ESSENTIAL OILS BY DOWNREGULATION NRF-2 AND MMP-9 IN BREAST CANCER | en_US |
dc.type | conferenceObject | en_US |
dc.description.version | Published | en_US |
dc.identifier.doi | 10.46793/SBT29.71AO | en_US |
dc.type.version | PublishedVersion | en_US |
Налази се у колекцијама: | Faculty of Science, Kragujevac |
Датотеке у овој ставци:
Датотека | Опис | Величина | Формат | |
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71-Obradovic et al.pdf | 505.84 kB | Adobe PDF | Погледајте |
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