Please use this identifier to cite or link to this item:
Title: Coupled computer modeling of atherosclerosis development in the coronary arteries
Authors: Isailovic, Velibor
Milosevic Z.
Nikolic, Dalibor
Saveljic I.
Nikolic, Milica
Gacic M.
Cirkovic-Andjelkovic B.
Themis E.
Fotiadis D.
Pelosi, Gualtiero
Parodi O.
Filipovic, Nenad
Journal: Proceedings - 2017 IEEE 17th International Conference on Bioinformatics and Bioengineering, BIBE 2017
Issue Date: 1-Jul-2017
Abstract: © 2017 IEEE. Atherosclerosis is characterized by dysfunction of endothelium, vasculitis and accumulation of lipid, cholesterol and cell elements inside blood vessel wall. Determination of plaque location and plaque volume for a specific patient is very important for prediction of atherosclerotic disease progression. In this study coupled computer modeling of atherosclerosis progression is analysed. Continuum approach assumed mass transport of LDL through the wall and the simplified inflammatory process coupled with three addi-tional reaction-diffusion equations and lesion growth model in the intima. Discrete modeling used dissipative particle dynamics method which individual blood constituents (e.g., platelets, RBCs, white blood cells) treated as particle interaction. Coupled continuum and discrete model was investigated with real patient baseline and follow up study for right and left coronary arteries.
Type: Conference Paper
DOI: 10.1109/BIBE.2017.00-19
SCOPUS: 85049513965
Appears in Collections:Faculty of Engineering, Kragujevac
Institute for Information Technologies, Kragujevac
[ Google Scholar ]

Page views(s)




Files in This Item:
File Description SizeFormat 
  Restricted Access
29.86 kBAdobe PDFThumbnail
View/Open Request a copy

Items in SCIDAR are protected by copyright, with all rights reserved, unless otherwise indicated.