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Назив: Species of genus Ganoderma (Agaricomycetes) fermentation broth: A novel antioxidant and antimicrobial agent
Аутори: Ćilerdžić J.
Kosanic, Marijana
Stajić M.
Vukojevic, Jelena
Ranković B.
Датум издавања: 2016
Сажетак: © 2016 Begell House, Inc. The bioactivity of Ganoderma lucidum basidiocarps has been well documented, but there are no data on the medicinal properties of its submerged cultivation broth nor on the other species of the genus Ganoderma. Thus the aim of this study was to test the potential antimicrobial and antioxidant activity of fermentation broth obtained after submerged cultivation of G. applanatum, G. carnosum, and G. lucidum. DPPH• scavenging ability, total phenols, and flavonoid contents were measured to determine the antioxidative potential of Ganoderma spp. fermentation filtrates, whereas their antimicrobial potential was studied using the microdilution method. DPPH• scavenging activity of G. lucidum fermentation filtrates was significantly higher than that of G. applanatum and G. carnosum, with the maximum (39.67%) obtained from strain BEOFB 432. This filtrate also contained the highest concentrations of phenols (134.89 µg gallic acid equivalents/mL) and flavonoids (42.20 µg quercetin equivalent/mL). High correlations between the activity and phenol content in the extracts showed that these compounds were active components of the antioxidative activity. G. lucidum strain BEOFB 432 was the most effective antibacterial agent, whereas strain BEOFB 434 has proven to be the most effective antifungal agent. The study showed that Ganoderma spp. fermentation filtrates are novel potent antioxidative and antimicrobial agents that could be obtained more quickly and cheaper than basidiocarps.
URI: https://scidar.kg.ac.rs/handle/123456789/11872
Тип: article
DOI: 10.1615/IntJMedMushrooms.v18.i5.30
ISSN: 1521-9437
SCOPUS: 2-s2.0-84984910855
Налази се у колекцијама:Faculty of Science, Kragujevac

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