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Title: Histamine blood concentration in ischemic heart disease patients
Authors: Rosic, Mirko
Zdravkovic, Vladimir
Pantović S.
Rosic, Gvozden
Tomic Lucic, Aleksandra
Zdravkovic, Nemanja
Colic M.
Obradović Z.
Issue Date: 2011
Abstract: The aim of this study was to investigate histamine blood concentration in subjects suffering from different types of ischemic heart diseases during the period of eight days. Our results showed that the histamine blood level was associated with different types of ischemic heart diseases. The blood histamine level in all investigated patients was significantly higher when compared to control subjects (44.87 ± 1.09ngmL -1), indicating the increase of histamine release in patients suffering from coronary diseases. In patients suffering from ACS-UA and ACS-STEMI, the second day peak of histamine level occurs (90.85 ± 6.34ngmL -1 and 121.7 ± 6.34ngmL -1, resp.) probably as the reperfusion event. Furthermore, our data suggest that histamine can be additional parameter of myocardial ischemia along with cardiac specific enzymes and may prove to be an excellent single prognostic marker for multitude of ischemic heart diseases. Copyright © 2011 Vladimir Zdravkovic et al.
Type: article
DOI: 10.1155/2011/315709
ISSN: 1110-7243
SCOPUS: 2-s2.0-80052687393
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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