Synthesis, cytotoxic activity, and thermal studies of novel N-[(1,3-diphenylpyrazol-4-yl)methyl] α-amino acids

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Назив:	Synthesis, cytotoxic activity, and thermal studies of novel N-[(1,3-diphenylpyrazol-4-yl)methyl] α-amino acids
Аутори:	Joksović, Milan Bogdanovic, Gordana Kojić, Vesna Mészáros Szécsényi, Katalin Leovac V. Jakimov, Dimitar Trifunović, Snežana Marković, Violeta Joksović, Ljubinka
Датум издавања:	2010
Сажетак:	(Chemical Equation Presented) New N-[(1,3-diphenylpyrazol-4-yl)methyl]a- amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential. © 2010 HeteroCorporation.
URI:	https://scidar.kg.ac.rs/handle/123456789/10201
Тип:	article
DOI:	10.1002/jhet.400
ISSN:	0022-152X
SCOPUS:	2-s2.0-77954598700
Налази се у колекцијама:	Faculty of Science, Kragujevac