Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке: https://scidar.kg.ac.rs/handle/123456789/10709
Назив: The role of NK cells in cancer
Аутори: Jurisic, Vladimir
Vuletić A.
Mirjacic Martinović K.
Konjević G.
Датум издавања: 2020
Сажетак: © Springer Nature Switzerland AG 2020. Although NK cells were initially discovered and named for their spontaneous ability to kill tumor cells, the knowledge of NK cells has grown to include not only their cytotoxic but also their immunoregulatory function, as well as characterization of many new activating and inhibitory receptors whose balance regulates their activity. In this sense, through recognition of cognate ligands on tumor cells by these receptors NK cells are able to distinguish transformed from normal cells. However, immunosuppressive factors produced by tumors affect NK cell receptor repertoire and lead to impaired NK cell function that facilitates tumor immune escape and disease progression. Better understanding of alterations in NK cell receptor expression, disturbance in NK cell activation, and effectors function in cancer patients may aid in defining novel biomarkers of disease as well as in creating many new immunotherapeutic strategies that potentiate NK cell antitumor activity.
URI: https://scidar.kg.ac.rs/handle/123456789/10709
Тип: bookPart
DOI: 10.1007/978-3-030-30845-2_9
SCOPUS: 2-s2.0-85086205469
Налази се у колекцијама:Faculty of Medical Sciences, Kragujevac

Број прегледа

165

Број преузимања

6

Датотеке у овој ставци:
Датотека Опис ВеличинаФормат 
PaperMissing.pdf
  Ограничен приступ
29.86 kBAdobe PDFСличица
Погледајте


Ставке на SCIDAR-у су заштићене ауторским правима, са свим правима задржаним, осим ако није другачије назначено.