A camphor based 1,3-diamine Ru(ii) terpyridine complex: Synthesis, characterization, kinetic investigation and DNA binding

Abstract

© 2018 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. The synthesis and reactivity of a new ruthenium(ii) terpyridine complex with a bidentate enantiopure camphor based diamine ligand is described. Reactivity measurements of the Ru(ii) complex showed a high affinity towards guanosine-5′-monophosphate as a model for DNA bases. Furthermore, the Ru(ii) complex was found to interact with CT-DNA. This suggests the high potential of the newly synthesized ruthenium complex as an antitumor agent.