MATHEMATICAL MODELING OF TOTAL FLAVONOID COMPOUNDS EXTRACTION FROM DILL (Anethum graveolens L.) LEAVES

Abstract

In this paper, extraction of the total flavonoid compounds from dill (Anethum graveolens L) leaves using an aqueous ethanol solution (50% by volume) was studied at different temperatures (30, 40, and 50 0C). A physical unsteady- state diffusion model and empirical Ponomarev model were developed to model the extraction process’s kinetics. The enthalpy and entropy changes were positive, while the Gibbs free energy was negative and decreased when temperature increased during the thermodynamic analysis. Therefore, extraction of total flavonoids from dill leaves was endothermic, spontaneous, and irreversible.