Modelling of Monocytes Behaviour inside the Bioreactor

Abstract

The developed model of bioreactor was used for simulation of the monocyte cells movement inside the bioreactor. Trajectories and concentration of the monocytes over time are in good agreement with the experimental measurements and the results obtained with two different finite element solvers,PAK and ANSYS,matched as well. The presented model of bioreactor and monocytes is a good starting point in further analysis of the monocytes. The next model will include modelling of a chemical reaction and binding of monocytes to the bottom of the bioreactor,in order to present the inflammatory process and reaction of the immune system.