CARDIOPROTECTIVE EFFECTS OF LADY’S BEDSTRAW EXTRACT: FOCUS ON OXIDATIVE STRESS

Abstract

Beside the widespread traditional use of Lady's Bedstraw in the treatment of numerous diseases and conditions, itʼs effects on heart function and redox status has still not been fully clarified. The aim of our study was to examine the effects of methanol extract of Lady's Bedstraw on oxidative stress parameters during on ischemia-reperfusion (I/R) injury in isolated rat heart. Our results demonstrated that treatment with methanol extract of Lady's Bedstraw preserved diminished production of many prooxidants. Promising potential of Lady's Bedstraw in the present study in a model of pharmacological preconditioning may be a starting point for future researches.