An Enhanced Method for Quantifying Energy Loss due to Diffusion in Coronary Arteries with Stenosis

Abstract

Energy loss in stenotic coronary arteries significantly affects blood flow efficiency and contributes to the development of ischemic heart disease. Various methods are employed to diagnose coronary artery stenosis and assess its functional significance, among which Fractional Flow Reserve (FFR) plays a key role. FFR quantifies the pressure drop caused by a stenosis in a coronary artery. Numerous studies have shown that the pressure drop due to diffusion constitutes the dominant component of total pressure loss in coronary stenosis, highlighting the importance of its reliable quantification. This paper presents an enhanced method for calculating the diffusive pressure drop, validated through the studies reported in [1] and [2].