Abo blood group and risk of glioma: A case control study from serbia

Abstract

© 2019, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved. Backgraund/Aim. Gliomas are the most common primary brain tumors and the etiology is unknown. The aim of this study was to investigate possible association between incidence in relation to glioma and certain blood groups. Methods. The case-control study included 100 pathologically confirmed cases of glioma at the Clinical centar of Kragujevac, Serbia, between 2014 and 2015, and 200 age- and sex-matched controls without malignant diseases in personal and family history at the same institution. After signing the informed consent, all patients filled out an epidemiological questionnaire. Results. In the analysis comparing the glioma patients with the control group, a significant association (p < 0.0005) was observed in relation to the blood group AB. Furthermore, it was not observed a significant association in relation to the blood group A (p = 0.070), blood group B (p = 0.256), blood group O (p = 0.768) among the compared groups. Also, in the analysis comparing glioma patients with the control group, a significant association was observed in relation to the years spent.