Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке: https://scidar.kg.ac.rs/handle/123456789/9322
Назив: Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation
Аутори: Lukovic D.
Moreno-Manzano V.
Lopez-Mocholi E.
Rodríguez-Jiménez F.
Jendelova P.
Syková E.
Oria, Marc
Stojkovic, Miodrag
Erceg S.
Датум издавања: 2015
Сажетак: © 2015, Nature Publishing Group. All rights reserved. Spinal cord injury (SCI) results in neural loss and consequently motor and sensory impairment below the injury. There are currently no effective therapies for the treatment of traumatic SCI in humans. Various animal models have been developed to mimic human SCI. Widely used animal models of SCI are complete or partial transection or experimental contusion and compression, with both bearing controversy as to which one more appropriately reproduces the human SCI functional consequences. Here we present in details the widely used procedure of complete spinal cord transection as a faithful animal model to investigate neural and functional repair of the damaged tissue by exogenous human transplanted cells. This injury model offers the advantage of complete damage to a spinal cord at a defined place and time, is relatively simple to standardize and is highly reproducible.
URI: https://scidar.kg.ac.rs/handle/123456789/9322
Тип: article
DOI: 10.1038/srep09640
SCOPUS: 2-s2.0-84928038441
Налази се у колекцијама:Faculty of Medical Sciences, Kragujevac

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