Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/10433
Title: Mesenchymal Stem Cells for Diabetes and Related Complications
Authors: Volarevic, Vladislav
lako, majlinda
Stojkovic, Miodrag
Issue Date: 2013
Abstract: © Springer Science+Business Media Dordrecht 2013. Mesenchymal stem cells (MSCs) are self-renewing cells with multipotent differentiation characteristics and capability for the regulation of immune response. Accordingly, in the context of diabetes research, the ability of MSC to generate insulin-producing cells and to enhance islet engraftment and survival makes them attractive as new therapeutic agents for treatment of diabetes and related complications. In this chapter we emphasized the role of MSCs in the repair of cell mass and function and we described the capacity of MSCs to modulate the autoimmune response during the pathogenesis of diabetes mellitus. In addition, we also presented here the mechanisms, promises and potential obstacles for MSC therapy of diabetic complications: cardiomyopathy, critical limb ischemia, nephropathy, polyneuropathy, retinopathy and diabetic wounds.
URI: https://scidar.kg.ac.rs/handle/123456789/10433
Type: bookPart
DOI: 10.1007/978-94-007-6716-4_14
SCOPUS: 2-s2.0-84907846816
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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