1. University of Kragujevac Digital Archive
  2. University of Kragujevac
  3. Faculty of Medical Sciences, Kragujevac
Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/10553
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dc.contributor.authorJurisic, Vladimir-
dc.contributor.authorČolović N.-
dc.contributor.authorTerzić D.-
dc.contributor.authorDjordjevic V.-
dc.contributor.authorColovic, Mirjana-
dc.date.accessioned2021-04-20T16:02:59Z-
dc.date.available2021-04-20T16:02:59Z-
dc.date.issued2012-
dc.identifier.issn0344-0338-
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/10553-
dc.description.abstractA 56-year-old male with chronic idiopathic myelofibrosis and cytogenetic finding of 20q- after a period of 10 months developed acute Philadelphia-positive lymphoblastic leukemia. Immunophenotyping of peripheral blood by flow cytometry showed HLA-DR, CD34, CD19, CD22, CD10, CD33, and CD11b positivity. Cytogenetic analysis revealed the presence of 20q- and Philadelphia chromosome t(9;22)(q34:q11) at the time of disease transformation to ALL. The JAK2V617F mutation was not found. This is a very rare case of simultaneous presence of two cytogenetics abnormalities and evolution of primary idiopathic myelofibrosis to Philadelphia-positive acute lymphoblastic leukemia. © 2012 Elsevier GmbH.-
dc.rightsrestrictedAccess-
dc.sourcePathology Research and Practice-
dc.titleTransformation of primary myelofibrosis with 20q- in Philadelphia-positive acute lymphoblastic leukemia: Case report and review of literature-
dc.typearticle-
dc.identifier.doi10.1016/j.prp.2012.04.007-
dc.identifier.scopus2-s2.0-84863815856-
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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