Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/12917
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dc.contributor.authorJovanovic D.-
dc.contributor.authorMilovanovic, Dragan-
dc.contributor.authorJovanovic I.-
dc.contributor.authorFolic, Marko-
dc.contributor.authorJakovljevic V.-
dc.date.accessioned2021-04-20T22:04:53Z-
dc.date.available2021-04-20T22:04:53Z-
dc.date.issued2020-
dc.identifier.issn0390-6663-
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/12917-
dc.description.abstract© 2020 Jovanovic et al. Purpose of Investigation: The relationships between postoperative recovery and changes of circulating levels of pro- and anti-in- flammatory cytokines. Materials and Methods: The study included prospectively a cohort of 51 females who underwent abdominal hys- terectomy for benign diseases. Recovery was assessed with Quality of Recovery 40 (QoR-40) questionnaire and concentrations of four cytokines during the 72-hours period were measured using human sensitive enzyme-linked immunosorbent assay (ELISA) kits. Results: Total QoR-40 score significantly declined on the first and the second postoperative days and then returned to baseline (p < 0.001). Interleukin-17 serum levels had no significant trend (p = 0.072). Statistically significant patterns of concentration changes of interferon gamma (p = 0.010), interleukin-10 (p < 0.001), and transforming growth factor (p = 0.016) were found. There were no significant cor- relations between QoR-40 scores and concentrations of any cytokine, at prespecified study power for moderate relationships at least. Conclusion: Recovery after abdominal hysterectomy was rapid and complete and it was unrelated to serum concentration profiles of examined cytokines.-
dc.rightsrestrictedAccess-
dc.sourceClinical and Experimental Obstetrics and Gynecology-
dc.titleInfluence of cytokines on the postoperative period-
dc.typearticle-
dc.identifier.doi10.31083/j.ceog.2020.01.4963-
dc.identifier.scopus2-s2.0-85082139356-
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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