Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке: https://scidar.kg.ac.rs/handle/123456789/13680
Пун извештај метаподатака
Поље DC-а ВредностЈезик
dc.rights.licenserestrictedAccess-
dc.contributor.authorMilovanovic, Jasmina-
dc.contributor.authorMilovanovic, Olivera-
dc.contributor.authorTomic Lucic, Aleksandra-
dc.contributor.authorDjokovic, Jelena-
dc.contributor.authorCvetkovic O.-
dc.contributor.authorŽivanović, Slavoljub-
dc.contributor.authorBarjaktarevic A.-
dc.contributor.authorPantović M.-
dc.contributor.authorRadovanovic, Milan-
dc.contributor.authorDimitrijevic, Aleksandra-
dc.contributor.authorJankovic A.-
dc.contributor.authorVeličković-Radovanović R.-
dc.date.accessioned2021-09-24T23:15:56Z-
dc.date.available2021-09-24T23:15:56Z-
dc.date.issued2021-
dc.identifier.issn0363-0242-
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/13680-
dc.description.abstractOptimal vitamin D status is very important for reflecting not only bone but overall woman’s health. The aim of the study was to determine pharmacokinetic variability of 25-hydroxy vitamin D, to reveal and quantify the most significant factors that affect its variability in the population of healthy non-menopausal women using the population pharmacokinetic (PopPK) approach. The study population consisted of 74 healthy reproductive women aged from 35 to 50 years, without the use of any supplement. A population pharmacokinetics analysis was conducted using a nonlinear mixed-effects model software. A total of 35 factors were assessed: demographic, clinical, biochemical data and lifestyle factors. The average age and bodyweight of our participants were 40.11 ± 4.35 years 65.30 ± 6.80 kg, respectively. The observed mean serum concentration of 25-hydroxy vitamin D was 26.51 ± 13.49 ng/mL with a wide range of 6.97 to 59.89 ng/mL. Development final PopPK model of the clearance of 25-hydroxy vitamin D showed that only the average daily dose of vitamin D intake from food had a significant influence, with a magnitude of its effects of 0.00401. These results could help when individualizing vitamin D intake in the form of supplements, especially during the wintertime, in healthy reproductive women.-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.sourceWomen and Health-
dc.titleThe significant role of dietary intake of vitamin D in non-menopausal women health-
dc.typearticle-
dc.identifier.doi10.1080/03630242.2021.1917480-
dc.identifier.scopus2-s2.0-85105166528-
Налази се у колекцијама:Faculty of Medical Sciences, Kragujevac

Број прегледа

932

Број преузимања

17

Датотеке у овој ставци:
Датотека Опис ВеличинаФормат 
PaperMissing.pdf
  Ограничен приступ
29.86 kBAdobe PDFСличица
Погледајте


Ставке на SCIDAR-у су заштићене ауторским правима, са свим правима задржаним, осим ако није другачије назначено.