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Title: In-silico Research Platform in the Cloud - Performance and Scalability Analysis
Authors: Ivanović, Miloš
Zivic, Andreja
Tachos, Nikolaos
Gois, George
Filipovic, Nenad
Fotiadis, Dimitrios
Issue Date: 2021
Abstract: The paper describes experiences from building and cloudification of the in-silico research platform SilicoFCM, an innovative in-silico clinical trials' solution for the design and functional optimization of whole heart performance and monitoring effectiveness of pharmacological treatment, with the aim to reduce the animal studies and the human clinical trials. The primary aim of cloudification was to prove portability, improve scalability and reduce long-term infrastructure costs. The most computationally expensive part of the platform, the scientific workflow manager, was successfully ported to Amazon Web Services. We benchmarked the performance on three distinct research workflows, each of them having different resource requirements and execution time. The first benchmark was pure performance of running workflow sequentially. The aim of the second test was to stress-test the underlying infrastructure by submitting multiple workflows simultaneously. The benchmark results are promising, painting the infrastructure launching overhead almost negligible in this kind of heavy computational use-case.
Type: conferenceObject
DOI: 10.1109/BIBE52308.2021.9635574
Appears in Collections:Faculty of Science, Kragujevac

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