Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке: https://scidar.kg.ac.rs/handle/123456789/8960
Назив: Stem cells and labeling for spinal cord injury
Аутори: Gazdic, Marina
Volarevic, Vladislav
Arsenijevic A.
Erceg S.
Moreno-Manzano V.
Arsenijevic, Nebojsa
Stojkovíc M.
Датум издавања: 2017
Сажетак: © 2016 by the authors; licensee MDPI, Basel, Switzerland. Spinal cord injury (SCI) is a devastating condition that usually results in sudden and long-lasting locomotor and sensory neuron degeneration below the lesion site. During the last two decades, the search for new therapies has been revolutionized with the improved knowledge of stem cell (SC) biology. SCs therapy offers several attractive strategies for spinal cord repair. The transplantation of SCs promotes remyelination, neurite outgrowth and axonal elongation, and activates resident or transplanted progenitor cells across the lesion cavity. However, optimized growth and differentiation protocols along with reliable safety assays should be established prior to the clinical application of SCs. Additionally, the ideal method of SCs labeling for efficient cell tracking after SCI remains a challenging issue that requires further investigation. This review summarizes the current findings on the SCs-based therapeutic strategies, and compares different SCs labeling approaches for SCI.
URI: https://scidar.kg.ac.rs/handle/123456789/8960
Тип: review
DOI: 10.3390/ijms18010006
ISSN: 1661-6596
SCOPUS: 2-s2.0-85008177084
Налази се у колекцијама:Faculty of Medical Sciences, Kragujevac

Број прегледа


Број преузимања


Датотеке у овој ставци:
Датотека Опис ВеличинаФормат 
10.3390-ijms18010006.pdf3.49 MBAdobe PDFСличица

Ова ставка је заштићена лиценцом Креативне заједнице Creative Commons