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Title: Stem cells as new agents for the treatment of infertility: Current and future perspectives and challenges
Authors: Volarevic, Vladislav
Bojic, Sanja
Nurkovic J.https
Volarevic, Ana
Ljujic, Biljana
Arsenijevic, Nebojsa
lako, majlinda
Stojkovíc M.
Journal: BioMed Research International
Issue Date: 1-Jan-2014
Abstract: Stem cells are undifferentiated cells that are present in the embryonic, fetal, and adult stages of life and give rise to differentiated cells that make up the building blocks of tissue and organs. Due to their unlimited source and high differentiation potential, stem cells are considered as potentially new therapeutic agents for the treatment of infertility. Stem cells could be stimulated in vitro to develop various numbers of specialized cells including male and female gametes suggesting their potential use in reproductive medicine. During past few years a considerable progress in the derivation of male germ cells from pluripotent stem cells has been made. In addition, stem cell-based strategies for ovarian regeneration and oocyte production have been proposed as future clinical therapies for treating infertility in women. In this review, we summarized current knowledge and present future perspectives and challenges regarding the use of stem cells in reproductive medicine. © 2014 Vladislav Volarevic et al.
Type: Review
DOI: 10.1155/2014/507234
ISSN: 23146133
SCOPUS: 84899995333
Appears in Collections:Faculty of Medical Sciences, Kragujevac
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