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Title: Probability of bystander effect induced by alpha-particles emitted by radon progeny using the analytical model of tracheobronchial tree
Authors: Jovanović, Boris
Nikezic, Dragoslav
Issue Date: 2010
Abstract: Radiation-induced biological bystander effects have become a phenomenon associated with the interaction of radiation with cells. There is a need to include the influence of biological effects in the dosimetry of the human lung. With this aim, the purpose of this work is to calculate the probability of bystander effect induced by alpha-particle radiation on sensitive cells of the human lung. Probability was calculated by applying the analytical model cylinder bifurcation, which was created to simulate the geometry of the human lung with the geometric distribution of cell nuclei in the airway wall of the tracheobronchial tree. This analytical model of the human tracheobronchial tree represents the extension of the ICRP 66 model, and follows it as much as possible. Reported probabilities are calculated for various targets and alpha-particle energies. Probability of bystander effect has been calculated for alpha particles with 6 and 7.69 MeV energies, which are emitted in the 222Rn chain. The application of these results may enhance current dose risk estimation approaches in the sense of the inclusion of the influence of the biological effects. © The Author 2010. Published by Oxford University Press. All rights reserved.
Type: article
DOI: 10.1093/rpd/ncq277
ISSN: 0144-8420
SCOPUS: 2-s2.0-78851472391
Appears in Collections:Faculty of Science, Kragujevac

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