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Title: Risk factors for recurrent vulvovaginal candidiasis
Authors: Jankovic, Slobodan
Bojović, Dragica
Vukadinovic, Dubravka
Daglar, Emina
Jankovic, Marija
Laudanovic, Dragomir
Lukić, Vladan
Mišković, Vesna
Potpara, Zorica
Projovic, Ivana
Čokanović, Vesna
Petrović, Nadežda
Folic, Marko
Savić, Viktorija
Issue Date: 2010
Abstract: Background/Aim. Recurrent vulvovaginal candidiasis is relatively frequent condition, and may have serious health consequences, like chronic vulvovaginal pain syndrome. The aim of our study was to determine possible risk factors for recurrent vulvovaginal candidiasis in non-pregnant females within the reproductive age. Methods. The design of our study was of a case-control type. Case and control patients were selected from the gynecological patients at six primary care facilities in Serbia and in Montenegro. The data on the patients' health condition, concomitant therapy and diseases were taken from their records, and the data on habits were obtained by unstructured interview. For potential risk factors crude odds ratios were calculated, and then adjusted by logistic regression. Results. A total of fifty-one patients had four or more episodes of vulvovaginal candidiasis during the last year (cases), and 132 patients with one to three episodes of vulvovaginal candidiasis were sampled as controls, matched by age. The only two significant associations were found between recurrent vulvovaginal candidiasis and continual wearing of panty liners during the last year (Odds ratio - ORadjusted: 3.97; confidence interval - CI: 1.57-10.02; p = 0.004), and between recurrent vulvovaginal candidiasis and predominant use of vaginal tampons during menstruation in the last year (ORadjusted: 4.25; CI: 1.11-16.27; p = 0.035). The synergistic effect was observed for the concurrent continual wearing of panty liners during the last year and selfmedication with antimycotics. Conclusions. Local factors, like wearing of panty liners or use of tampons during menstruation, may promote recurrence of vulvovaginal candidiasis, especially in patients who practice selfmedication with antimycotics.
Type: article
DOI: 10.2298/VSP1010819J
ISSN: 0042-8450
SCOPUS: 2-s2.0-78149290331
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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