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Title: Synthesis and antimicrobial activity of new 4-heteroarylamino coumarin derivatives containing nitrogen and sulfur as heteroatoms
Authors: Dekić, Biljana
Radulovic, Niko
Dekić, Vidosav
Vukicevic, Rastko
Palić Radosav
Issue Date: 2010
Abstract: Synthesis, spectral analysis and bioactivity of new coumarin derivatives are described in this paper. Eight new coumarin derivatives were synthesized in moderate to good yields by condensation of 4-chloro-3-nitrocoumarin and the corresponding heteroarylamine. The synthesized compounds were tested for their in vitro antimicrobial activity, in a standard disk diffusion assay, against thirteen strains of bacteria and three fungal strains. They have shown a wide range of activity - from one completely inactive compound to medium active ones. Copyright © 2010 by the authors.
Type: article
DOI: 10.3390/molecules15042246
SCOPUS: 2-s2.0-77951838172
Appears in Collections:Faculty of Science, Kragujevac

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