Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/10237
Title: An efficient synthesis and antioxidant properties of novel imino and amino derivatives of 4-hydroxy coumarins
Authors: Vukovic, Nenad
Sukdolak S.
Solujic A.
Martinović, Neda
Issue Date: 2010
Abstract: Series of imino and amino derivatives of 4-hydroxy coumarins were synthesized via conventional and microwave promoted procedure and evaluated for antioxidant potential through different in vitro models such as (DPPH) free radical scavenging activity, linoleic acid emulsion model system, reducing power assay and phosphomolybdenum method. All prepared compounds possess good antioxidant activity and among them p-nitro-phenyl derivative 6c with IC 50 at 25.9 μM possesses radical scavenging activity which is comparable to standard BHT, while the best reducing power was observed in a case of benzyl amino compound 8c (RP50 255.6 μM). Also, observed data indicated that compounds may serve as inhibitors of lipid peroxidation process. © 2010 The Pharmaceutical Society of Korea and Springer Netherlands.
URI: https://scidar.kg.ac.rs/handle/123456789/10237
Type: article
DOI: 10.1007/s12272-010-2220-z
ISSN: 0253-6269
SCOPUS: 2-s2.0-77949882295
Appears in Collections:Faculty of Science, Kragujevac

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