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Title: Epidemiology and risk factors for healthcare-associated infections caused by Pseudomonas aeruginosa
Authors: Folic, Marko
Djordjevic Z.
Folic N.
Radojevic M.
Jankovic, Slobodan
Issue Date: 2020
Abstract: © 2020 Edizioni Scientifi che per l'Informazione su Farmaci e Terapia. Pseudomonas aeruginosa (PA) is a globally recognized cause of healthcare-associated infections (HAIs). The aim of our cross-sectional study, conducted in a Serbian tertiary care hospital, was to investigate clinical characteristics of HAIs caused by the PA, the prevalence of various drug-resistant phenotypes of this pathogen, and risk factors for their occurrence. Prolonged ICU stay and previous carbapenem administration were independent risk factors for HAIs caused by carbapenem-resistant PA, while HAIs caused by multidrug-resistant PA were more frequent in patients with prolonged stay in an ICU, who were previously hospitalized at another department and previously treated with aminoglycosides, fluoroquinolones or glycopeptides. The prolonged ICU stay was the only significant risk factor for HAIs caused by extensively drug-resistant PA. To decrease the incidence of HAIs caused by drug-resistant PA, a multifaceted approach is necessary, including staff education, antibiotic stewardship, improving hygiene, shortening hospitalization, and minimizing exposure to invasive medical procedures/devices.
Type: article
DOI: 10.1080/1120009X.2020.1823679
ISSN: 1120-009X
SCOPUS: 2-s2.0-85091844735
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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