Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке: https://scidar.kg.ac.rs/handle/123456789/10616
Назив: Dipeptidyl peptidase-4 inhibitors as new tools for cardioprotection
Аутори: Rankovic M.
Jeremić N.
Srejovic I.
Radonjic K.
Stojanovic, Aleksandar
Glisic M.
Bolevich, Stephani Sergeevna
Bolevich, Sergey
Jakovljevic V.
Часопис: Heart Failure Reviews
Датум издавања: 1-јан-2020
Сажетак: © 2020, Springer Science+Business Media, LLC, part of Springer Nature. Previous studies have demonstrated that individuals with type 2 diabetes mellitus (T2DM) have a two- to fourfold propensity to develop cardiovascular disease (CVD) than nondiabetic population, making CVD a major cause of death and disability among people with T2DM. The present treatment options for management of diabetes propose the earlier and more frequent use of new antidiabetic drugs that could control hyperglycaemia and reduce the risk of cardiovascular events. Findings from basic and clinical studies pointed out DPP-4 inhibitors as potentially novel pharmacological tools for cardioprotection. There is a growing body of evidence suggesting that these drugs have ability to protect the heart against acute ischaemia-reperfusion injury as well as reduce the size of infarction. Consequently, the prevention of degradation of the incretin hormones by the use of DPP-4 inhibitors represents a new strategy in the treatment of patients with T2DM and reduction of CV events in these patients. Here, we discuss the cardioprotective effects of DPP-4 inhibitors as well as proposed pathways that these hypoglycaemic agents target in the cardiovascular system.
URI: https://scidar.kg.ac.rs/handle/123456789/10616
Тип: Review
DOI: 10.1007/s10741-020-10005-5
ISSN: 13824147
SCOPUS: 85088306197
Налази се у колекцијама:University Library, Kragujevac
[ Google Scholar ]

Број прегледа

19

Датотеке у овој ставци:
Датотека Опис ВеличинаФормат 
PaperMissing.pdf
  Ограничен приступ
29.86 kBAdobe PDFСличица
Погледајте    Захтев за копију


Ставке на SCIDAR-у су заштићене ауторским правима, са свим правима задржаним, осим ако није другачије назначено.