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Title: Malignant fibrous histiocytoma of the right upper leg – A case report
Authors: Pavlovic, Mladen
Milosevic, Bojan
Radovanovic D.
Cvetkovic, Aleksandar
Sredojević, Bratislav
Canovic D.
Mitrovic B.
Jovanovic M.
Spasic M.
Vulovič M.
Stojanovic B.
Jeremic, Dejan
Jevdjic, Jasna
Journal: Vojnosanitetski Pregled
Issue Date: 1-Mar-2018
Abstract: © 2018, Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved. Introduction. Malignant fibrous histiocytoma is a fast spreading pleomorphic sarcoma with a high malignant potential. Its spreading is characterized with local invasion and distant metastazes with early onset. Most common localisations of development are extremities, trunk and retroperitoneum. Given the line of rare case and specimen, lack of a clear etiology and mechanisms of this disease, as well as adequate histopathologic findings and intraoperative documentation, we presented current status, discuss putative etiology, histopathology with variant morphology, differential diagnosis and treatment modalities. Case report. We presented a 56-years-old female Serbian with tumor in the thigh that clinically resembles incapsulated hematoma. Computed tomography revealed intramuscular tumor with a heterodense structure and compression on surround tissue. Ex tempore biopsy specimen showed malignant potential of the tumor. Wide and radical excision of the nodule has been done, and definitive histopathological verification revealed malignant fibrous histiocytoma. Conclusion. Malignant fibrous histiocytoma is a most common type of soft tissue sarcomas in adults. Frequent localization is on lower extremities, and every rapidly enlarging nodule in this localization that on computed tomography is like incapsulated hematoma with necrotic zone should alert suspicion on presence of this type of sarcoma.
Type: Article
DOI: 10.2298/VSP160512237P
ISSN: 00428450
SCOPUS: 85046409083
Appears in Collections:Faculty of Medical Sciences, Kragujevac
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