Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/12198
Title: Onosma aucheriana: A source of biologically active molecules for novel food ingredients and pharmaceuticals
Authors: Mašković, Pavle
Diamanto L.
Vujic J.
Cvetanović, Aleksandra
Radojković M.
Gadzuric S.
Zengın G.
Issue Date: 2015
Abstract: © 2015 Elsevier Ltd. The phenolic profile, antioxidant activity and cytotoxicity of O. aucheriana aqueous extract were investigated. HPLC-DAD (high performance liquid chromatography-diode array detector) technique was used to define the profile of phenolic compounds of the resultant extract. Antioxidant properties were evaluated using different methods, including phosphomolybdenum, free radical scavenging and lipid peroxidation assays. Rosmarinic, gallic and p-hydroxybenzoic acids were determined as the major phenolic compounds. Human rhabdomyosarcoma (RD), human cervix carcinoma (Hep2c) and murine fibroblast (L2OB) cell lines were used to examine the cytotoxicity of the extract. The IC50 (inhibitory concentration at 50%) values ranged from 25.54 to 40.34 μg/mL. These results suggest that this species may be considered as a valuable candidate for preparing new food and drug formulations.
URI: https://scidar.kg.ac.rs/handle/123456789/12198
Type: article
DOI: 10.1016/j.jff.2015.09.054
ISSN: 1756-4646
SCOPUS: 2-s2.0-84946399978
Appears in Collections:Faculty of Agronomy, Čačak

Page views(s)

496

Downloads(s)

11

Files in This Item:
File Description SizeFormat 
PaperMissing.pdf
  Restricted Access
29.86 kBAdobe PDFThumbnail
View/Open


Items in SCIDAR are protected by copyright, with all rights reserved, unless otherwise indicated.