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Title: Contemporary surgical management of drug-resistant focal epilepsy
Authors: Milovanovic, Jasmina
Jankovic, Slobodan
Milovanovic, Dragan
Ruzic Zecevic, Dejana
Folic, Marko
Kostic M.
Ranković G.
Stefanovic, Srdjan
Issue Date: 2020
Abstract: © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Introduction: Seizures, which could not be controlled by drug therapy, have profound negative influence on the quality of life of the affected person. If with clear locus of origin and accompanied by loss of consciousness, drug-resistant epilepsy could be treated by surgery. Areas covered: The aim of this article was to review current status of epilepsy surgery through description of the most important operative methods and narrative comparison of their benefits and harms. In total 1154 articles were retrieved from MEDLINE, SCOPUS, EBSCO, and SCINDEKS databases, and 78 included in the review. The review included systematic reviews, meta-analyses, clinical trials, observational studies on humans, case series, and case reports. Expert opinion: Sophisticated diagnostic methods nowadays offer much more precise localization of epileptogenic focus and detailed planning of a surgical procedure which will make minimal damage of neural pathways and structures essential for movements, speech, cognition, and emotions. Advent of perioperative care, and improved diagnostics and surgical techniques resulted with significant drop in rates of postoperative complications, long-term neurological deficit, and mortality in the last decade, while seizure freedom rate and quality of life increased.
Type: review
DOI: 10.1080/14737175.2020.1676733
ISSN: 1473-7175
SCOPUS: 2-s2.0-85074520503
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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