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Title: Treating of focal epilepsy: A patent review
Authors: Jankovic, Slobodan
Marković N.
Luković K.
Journal: Pharmaceutical Patent Analyst
Issue Date: 1-May-2021
Abstract: Focal epilepsy is one of the most frequent specific type of epilepsies, with 30% treatment-resistant patients. There are several directions researchers can follow to improve existing treatment of focal epilepsy: synthesis of new compounds with anticonvulsant activity, repurposing drugs approved for other indications, finding drugs targeted to specific genetic and biochemical defects that underlie focal epilepsy syndromes, development of viral vectors for specific gene therapy, creation of devices and methods for suppression of seizures by electrostimulation and development of methods to increase safety of epilepsy surgery. Improvement of efficacy and safety of current therapies is necessary, as well as developing targeted treatment of genetic epilepsy syndromes that will not only suppress seizures, but stop further epileptogenesis.
Type: Review
DOI: 10.4155/ppa-2021-0008
ISSN: 20468954
SCOPUS: 85114069291
Appears in Collections:Faculty of Medical Sciences, Kragujevac
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