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Title: Amygdala Volumes in Autism Spectrum Disorders: Meta-analysis of Magnetic Resonance Imaging Studies
Authors: Kovacevic, Marija
Macuzic I.
Milosavljević J.
Lukovic B.
Aleksic, Dejan
Gavrilovic, Jagoda
Milosavljević, Miloš
Jankovic, Slobodan
Pejcic, Ana
Issue Date: 2021
Abstract: We conducted meta-analysis in order to determine if there are significant differences in left and right amygdala volume in individuals with autism spectrum disorders (ASD) compared to a control group. Twenty-three studies fulfilled inclusion criteria for our study. Right amygdala volume was significantly larger in ASD patients compared to controls (Hedges’ g 0.44; 95% CI 0.04–0.83; Z = 2.26; p = 0.024), while there was no significant difference in left amygdala volume between ASD patients and controls (Hedges’ g 0.44; 95% CI − 0.10–0.98; Z = 1.67; p = 0.095). However, between-study heterogeneity was significant so there is an unequivocal need for new uniform magnetic resonance imaging (MRI) studies to get a more precise answer to the question of whether there is a difference in amygdala volume between ASD patients and controls.
Type: article
DOI: 10.1007/s40489-021-00281-8
ISSN: 2195-7177
SCOPUS: 2-s2.0-85111079216
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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