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Title: CAR T Cell Therapy for Chronic Lymphocytic Leukemia: Successes and Shortcomings
Authors: Todorovic Z.
Jakovcev-Todorovic D.
Grbovic-Markovic V.
Ladjevac N.
Zdravković N.
Djurdjevic, Predrag
Arsenijevic, Nebojsa
Milovanovic, Marija
Arsenijevic A.
Milovanovic, Jelena
Journal: Current Oncology
Issue Date: 1-May-2022
Abstract: Chimeric antigen receptor T (CAR T) cell therapy achieved remarkable success in B-cell leukemia and lymphoma which led to its incorporation in treatment protocols for these diseases. CAR T cell therapy for chronic lymphocytic leukemia (CLL) patients showed less success compared to other malignant tumors. In this review, we discuss the published results regarding CAR T cell therapy of CLL, possible mechanisms of failures and expected developments.
Type: review
DOI: 10.3390/curroncol29050293
SCOPUS: 85130550535
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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