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dc.contributor.authorMatić, Sanja-
dc.contributor.authorCvetković, Vladimir-
dc.contributor.authorNikolić, Biljana-
dc.contributor.authorMitić, Zorica-
dc.date.accessioned2023-11-09T11:53:21Z-
dc.date.available2023-11-09T11:53:21Z-
dc.date.issued2023-
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/19362-
dc.description.abstractChamaecyparis lawsoniana (A.Murray bis) Parl., known as Port Orford cedar or Lawson cypress and Thuja plicata Donn ex D.Don, also called giant arborvitae, are a species of the Cupressaceae family. Multiple significant biological activities of C. lawsoniana and T. plicata essential oils have been widely investigated, but their genotoxic and/or antigenotoxic properties are not well established. In the present study, two in vitro antioxidant assays were performed to assess the possible DNA protective activity of five different concentrations (0.19, 0.38, 0.75, 1.5, and 3%) of essential oils against oxidative damage induced by hydroxyl and peroxyl radicals. According to the obtained results, both essential oils have a remarkable DNA protective activity against hydroxyl and peroxyl radicals induced DNA damage. These findings confirm that C. lawsoniana and T. plicata essential oils in tested concentrations could be valuable candidates for medicinal and pharmaceutical applications.en_US
dc.language.isoenen_US
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.source9th International Electronic Conference on Medicinal Chemistryen_US
dc.subjectAntigenotoxicityen_US
dc.subjectChamaecyparis lawsonianaen_US
dc.subjectessential oilsen_US
dc.subjecthydroxyl radicalen_US
dc.subjectperoxyl radicalen_US
dc.subjectThuja plicataen_US
dc.titleIn vitro DNA protective potential of Chamaecyparis lawsoniana (A.Murray bis) Parl. and Thuja plicata Donn ex D.Don essential oilsen_US
dc.typeconferenceObjecten_US
dc.description.versionPublisheden_US
dc.identifier.doi10.3390/ECMC2023-15677en_US
dc.type.versionPublishedVersionen_US
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