Synthesis of palladium(II) complex with 2-(phenylselenomethyl)tetrahydropyran

Abstract

The use of organoselenium compounds as ligands in transition metal coordination chemistry has deserved special attention, in part as a result of the recognition that they may confer significantly different properties on the resultant complexes [1]. In addition, many organoselenium compounds play important roles in biochemical processes, ranging from antioxidant, to anticancer and antiviral activities [2]. In order to study biological activity, Pd(II) complex with 2-(phenylselenomethyl) tetrahydropyran as ligand was synthesized. It is noteworthy to mention that this kind of ligand compounds can be easily obtained in high yields via phenylselenoetherification of corresponding unsaturated alcohols in the presence of additives, such as pyridine [3]. For synthetic procedure, PdCl2 and ligand were used in ratio 1:1. Single crystals were obtained after slow evaporation of complex compound from ethanol/methanol solvent system. The crystal and molecular structure of the complex [Pd(L)2)]Cl2 has been determined by X-ray diffraction. It turned out that two ligands are coordinated to the Pd via Se atom in trans-fashion and the other two trans position are occupied by Cl atoms.