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Title: Stem cells therapy for spinal cord injury
Authors: Gazdic, Marina
Volarevic, Vladislav
Randall Harrell C.
Fellabaum, Crissy
Jovicic, Nemanja
Arsenijevic, Nebojsa
Stojkovíc M.
Journal: International Journal of Molecular Sciences
Issue Date: 1-Apr-2018
Abstract: © 2018 by the authors. Licensee MDPI, Basel, Switzerland. Spinal cord injury (SCI), a serious public health issue, most likely occurs in previously healthy young adults. Current therapeutic strategies for SCI includes surgical decompression and pharmacotherapy, however, there is still no gold standard for the treatment of this devastating condition. Inefficiency and adverse effects of standard therapy indicate that novel therapeutic strategies are required. Because of their neuroregenerative and neuroprotective properties, stem cells are a promising tool for the treatment of SCI. Herein, we summarize and discuss the promising therapeutic potential of human embryonic stem cells (hESC), induced pluripotent stem cells (iPSC) and ependymal stem/progenitor cells (epSPC) for SCI.
Type: Review
DOI: 10.3390/ijms19041039
ISSN: 16616596
SCOPUS: 85045031075
Appears in Collections:Faculty of Medical Sciences, Kragujevac
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