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Title: Primary small cell carcinoma of lung with metachronous breast metastasis
Authors: Markovic M.
Jovanovic D.
Todorovic Z.
Zivkovic M.
Dagovic, Aleksandar
Mitrovic M.
Petrovic, Marina
Nesic, Jelena
Issue Date: 2017
Abstract: © 2017, University of Kragujevac, Faculty of Science. All rights reserved. Breast metastases from an extra-mammary malignancy are rare. Among the lung malignancies that metastasise in the breasts, previous literature has described approximately 30 cases of NSCLC and only a few cases of SCLC. Here, we present a 54-year-old woman with metachronous breast metastasis from pulmonary small cell carcinoma. She presented with a soft tissue mass in the right lung hilum. After bronchoscopy with biopsy, SCLC was verified. The patient was given 4 cycles of etoposide and cisplatin followed by radiation therapy. Seven months after the diagnosis of primary lung cancer, the patient palpated a mass in her right breast. Clinical examination and further diagnostics revealed the suspected malignancy, and a radical mastectomy was performed. Immunohistochemical findings suggested metastatic SCLC in the breast. Differentiation between primary and metastatic cancer in the breast is very important for therapeutic planning.
Type: article
DOI: 10.1515/SJECR-2016-0087
ISSN: 1820-8665
SCOPUS: 2-s2.0-85030677470
Appears in Collections:Faculty of Medical Sciences, Kragujevac

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