Please use this identifier to cite or link to this item:
https://scidar.kg.ac.rs/handle/123456789/8819
Title: | Protein Sequence Comparison Based on Physicochemical Properties and the Position-Feature Energy Matrix |
Authors: | Yu L. Zhang, Yusen ![]() Gutman, Ivan ![]() ![]() Shi, Yongtang ![]() Dehmer M. |
Issue Date: | 2017 |
Abstract: | © 2017 The Author(s). We develop a novel position-feature-based model for protein sequences by employing physicochemical properties of 20 amino acids and the measure of graph energy. The method puts the emphasis on sequence order information and describes local dynamic distributions of sequences, from which one can get a characteristic B-vector. Afterwards, we apply the relative entropy to the sequences representing B-vectors to measure their similarity/dissimilarity. The numerical results obtained in this study show that the proposed methods leads to meaningful results compared with competitors such as Clustal W. |
URI: | https://scidar.kg.ac.rs/handle/123456789/8819 |
Type: | article |
DOI: | 10.1038/srep46237 |
SCOPUS: | 2-s2.0-85017395202 |
Appears in Collections: | Faculty of Science, Kragujevac |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
10.1038-srep46237.pdf | 713.05 kB | Adobe PDF | ![]() View/Open |
This item is licensed under a Creative Commons License