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Title: Acid-Catalyzed [3+2] Cycloaddition of Enones with Azomethine Imines for Easy Access to Tetrahydropyrazolopyrazolones
Authors: Bugarinović, Jovana
Bogdanovic, Goran A.
Damljanović, Ivan
Journal: Synlett
Issue Date: 1-Apr-2017
Abstract: © Georg Thieme VerlagStuttgart · New York. Aluminum chloride (AlCl3) or zirconium chloride (ZrCl4) catalyzes efficiently the [3+2] cycloaddition of N,N′-cyclic azomethine imines with enones which contain the vinyl group. The scope of the reaction towards various azomethine imines and enones has been explored. Access to diastereomerically pure 6-acyl-5-aryltetrahydropyrazolo[1,2-a]pyrazol-1(5H)-ones is provided by easy chromatographic separations.
Type: Article
DOI: 10.1055/s-0036-1588678
ISSN: 09365214
SCOPUS: 85006416108
Appears in Collections:Faculty of Science, Kragujevac
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