Ovarian dysgerminoma

Abstract

© 2016, University of Kragujevac, Faculty of Science. All Rights Reserved. Ovarian dysgerminoma (OD) is one of the most common malignant tumours of the ovarian germ cells, comprising 1-2% of all malignant ovarian tumours. It most commonly occurs between the ages of 10 and 30. The treatment is primarily surgical; however, in the advanced stages of the disease, surgical treatment is followed by chemotherapy. We report a case of a 19-year-old female patient who was diagnosed with bilateral ovarian dysgerminoma. The patient was first operated for dysgerminoma on the left ovary and an ovariectomy was performed. A month later, she underwent surgery again because of the appearance of a residual tumour in the lodge of the removed ovary; the rest of the tumour was removed at that time. The histological finding was dysgerminoma ovarii, FIGO stage 1c. As agreed on by the consulting team, the patient returned for a follow-up ultrasound examination every three months. Nevertheless, nine months after the operation, she was diagnosed with dysgerminoma of the right ovary. Surgical treatment was performed again, and the tumour was removed. The histological finding on the second occasion was dysgerminoma ovarii, FIGO stage IIa, according to the TNM classification T2aNxMx. To preserve the reproductive capacity of the patient, the consulting team agreed to treat the patient with chemotherapy, i.e., 3 cycles of BEP [Bleomycin, Etoposide, Cisplatin (Platinum)]. Magnetic resonance imaging, ultrasound and clinical examination after the therapy were normal. The patient is monitored in regular intervals, feels good and has no signs of the disease after five years.