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Title: Antimicrobial activity, total phenolic content and flavonoid concentrations of Teucrium species
Authors: Stanković, Milan
Stefanović, Olgica
Čomić, Ljiljana
Topuzovic, Marina
Radojevic, Ivana
Solujic A.
Issue Date: 2012
Abstract: In vitro antimicrobial activity of 21 crude extracts obtained from seven taxa of the genus Teucrium (T. chamaedrys, T. montanum, T. arduini, T. polium, T. scordium subsp. scordium, T. scordium subsp. scordioides and T. botrys) was tested against bacterial and fungal species. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using a microdilution analysis method. Total phenolic content and flavonoid concentrations were measured spectrophotometrically. Total phenols were determined using Folin-Ciocalteu reagent and their amounts ranged from 28. 49 up to 159. 84 mg CA/g of extract (chlorogenic acid equivalent). The amounts of flavonoids ranged from 38. 17 up to 190. 45 mg RU/g of extract (rutin equivalent). The plant extracts showed greater potential of antibacterial than antifungal activity. A relationship was found between total phenolics and biological activity. The highest level of total phenols was measured in the methanol extracts, which demonstrated higher antimicrobial activity than acetone and ethyl acetate extracts. Staphylococcus aureus ATCC 25923 appeared to be the most sensitive organism. Our results indicate that Teucrium spp extracts are rich sources of phenolic compounds and are promising candidates for further development as natural antimicrobial agents. © 2012 Versita Warsaw and Springer-Verlag Wien.
Type: article
DOI: 10.2478/s11535-012-0048-x
ISSN: 1895-104X
SCOPUS: 2-s2.0-84861893450
Appears in Collections:Faculty of Science, Kragujevac

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