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https://scidar.kg.ac.rs/handle/123456789/9676
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DC Field | Value | Language |
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dc.rights.license | BY-NC-ND | - |
dc.contributor.author | Lee G. | - |
dc.contributor.author | Filipovic, Nenad | - |
dc.contributor.author | Lin M. | - |
dc.contributor.author | Gibney B. | - |
dc.contributor.author | Simpson D. | - |
dc.contributor.author | Konerding M. | - |
dc.contributor.author | TSUDA A. | - |
dc.contributor.author | Mentzer S. | - |
dc.date.accessioned | 2020-09-19T18:51:48Z | - |
dc.date.available | 2020-09-19T18:51:48Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1058-8388 | - |
dc.identifier.uri | https://scidar.kg.ac.rs/handle/123456789/9676 | - |
dc.description.abstract | To investigate the local mechanical forces associated with intravascular pillars and vessel pruning, we studied the conducting vessels in the extraembryonic circulation of the chick embryo. During the development days 13-17, intravascular pillars and blood flow parameters were identified using fluorescent vascular tracers and digital time-series video reconstructions. The geometry of selected vessels was confirmed by corrosion casting and scanning electron microscopy. Computational simulations of pruning vessels suggested that serial pillars form along pre-existing velocity streamlines; blood pressure demonstrated no obvious spatial relationship with the intravascular pillars. Modeling a Reynolds number of 0.03 produced 4 pillars at approximately 20-μm intervals matching the observed periodicity. In contrast, a Reynolds number of 0.06 produced only 2 pillars at approximately 63-μm intervals. Our modeling data indicated that the combination of wall shear stress and gradient of shear predicted the location, direction, and periodicity of developing pillars. © 2011 Wiley-Liss, Inc. | - |
dc.rights | openAccess | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.source | Developmental Dynamics | - |
dc.title | Intravascular pillars and pruning in the extraembryonic vessels of chick embryos | - |
dc.type | article | - |
dc.identifier.doi | 10.1002/dvdy.22618 | - |
dc.identifier.scopus | 2-s2.0-79955731137 | - |
Appears in Collections: | Faculty of Engineering, Kragujevac |
Files in This Item:
File | Description | Size | Format | |
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10.1002-dvdy.22618.pdf | 1.77 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License