1. University of Kragujevac Digital Archive
  2. University of Kragujevac
  3. Faculty of Science, Kragujevac
Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/10068
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dc.contributor.authorMarković, Violeta-
dc.contributor.authorEric Slavica-
dc.contributor.authorJuranić Z.-
dc.contributor.authorStanojkovic, Tatjana-
dc.contributor.authorJoksović, Ljubinka-
dc.contributor.authorRanković B.-
dc.contributor.authorKosanic, Marijana-
dc.contributor.authorJoksović, Milan-
dc.date.accessioned2021-04-20T14:47:17Z-
dc.date.available2021-04-20T14:47:17Z-
dc.date.issued2011-
dc.identifier.issn0045-2068-
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/10068-
dc.description.abstractA series of aminomethylidene derivatives obtained from 4-formyledaravone were synthesized and characterized by IR, NMR and elemental analysis. All the compounds were screened for their antitumor activity. The compound containing 5-phenylpyrazole moiety (3q) exhibited remarkable antitumor activity in in vitro assays, especially against human breast cancer MDA-MB-361 and MDA-MB-453 cell lines. The most important whole-molecule descriptors for antitumor activity on MDA-MB-453 cells belong to the group of quantum-chemical descriptors. © 2010 Elsevier Inc. All rights reserved.-
dc.rightsrestrictedAccess-
dc.sourceBioorganic Chemistry-
dc.titleSynthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone-
dc.typearticle-
dc.identifier.doi10.1016/j.bioorg.2010.10.003-
dc.identifier.scopus2-s2.0-78751647459-
Appears in Collections:Faculty of Science, Kragujevac

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