Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/10163
Title: Role of Galectin-3 in Tumour Metastasis
Authors: Radosavljevic, Gordana
Jovanovic I.
Knezevic M.
Zdravkovic, Nemanja
Pavlovic S.
Lukic, Miodrag
Arsenijevic, Nebojsa
Journal: Moscow University Chemistry Bulletin
Issue Date: 20-Sep-2010
Abstract: We used metastatic variant of B16 melanoma (B16F1) to study lung colonization galectin-3-deficient (gal-3-/-) C57BL/6 mice. In vivo study showed that compared with gal-3+/+ mice, gal-3-/-mice exhibited resistance to lung colonization of B16F1 melanoma cells (p < 0.03). In vitro assays showed higher number of attached malignant cells in the tissue section derived from gal-3+/+ mice (p < 0.001) and tumor specific cytotoxicity of lymphoid cells of tumour inoculated gal-3-/- suggesting that galectin-3 is considered as therapeutic target. © 2010 Allerton Press, Inc.
URI: https://scidar.kg.ac.rs/handle/123456789/10163
Type: journal article
DOI: 10.3103/S0027131410030107
ISSN: 00271314
SCOPUS: 77956608737
Appears in Collections:Faculty of Medical Sciences, Kragujevac

Page views(s)

57

Downloads(s)

1

Files in This Item:
File Description SizeFormat 
PaperMissing.pdf
  Restricted Access
29.86 kBAdobe PDFThumbnail
View/Open


Items in SCIDAR are protected by copyright, with all rights reserved, unless otherwise indicated.