Please use this identifier to cite or link to this item: https://scidar.kg.ac.rs/handle/123456789/10641
Title: Numerical analysis of plaque progression in 3d patient specific model of carotid artery
Authors: Djorovic S.
Saveljic I.
Filipovic, Nenad
Journal: IFMBE Proceedings
Issue Date: 1-Jan-2020
Abstract: © Springer Nature Switzerland AG 2020. The main purpose of this study was to computationally examine the hemodynamic parameters of plaque progression within carotid artery, such as wall shear stress and plaque concentration. The 3D finite element mesh was created for a patient-specific anatomical geometry which was reconstructed on the basis of computed tomography (CT) scan images. The 3D blood flow was governed by the Navier–Stokes equations and continuity equation. Mass transfer within the blood lumen and through the arterial wall was coupled with the blood flow and modelled by the convection–diffusion equation. Kedem–Katchalsky equations described low-density lipoprotein (LDL) transport in lumen of the vessel. Two time periods were considered (baseline and follow-up). The results of the analyzes have shown that zones with lower shear stress values were correlated with the zones of plaque accumulation and progression. This was confirmed at the follow-up, where simulation results had shown that carotid lumen was reduced due to plaque progression. This type of numerical simulations has become significant support to medicine, due to capability to determine the zone of plaque appearance and predict its further progression.
URI: https://scidar.kg.ac.rs/handle/123456789/10641
Type: Conference Paper
DOI: 10.1007/978-3-030-17971-7_52
ISSN: 16800737
SCOPUS: 85066012011
Appears in Collections:Faculty of Engineering, Kragujevac
[ Google Scholar ]

Page views(s)

14

Files in This Item:
File Description SizeFormat 
PaperMissing.pdf
  Restricted Access
29.86 kBAdobe PDFThumbnail
View/Open Request a copy


Items in SCIDAR are protected by copyright, with all rights reserved, unless otherwise indicated.