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Title: Preparation and antimicrobial activity of a new palladium(II) complexes with a coumarin-derived ligands. Crystal structures of the 3-(1-(o-toluidino)ethylidene)-chroman-2,4-dione and 3-(1-(m-toluidino) ethylidene)-chroman-2,4-dione
Authors: Avdović, Edina
Stojković, Danijela
Jevtić, Verica
Milenkovic, Dejan
Marković, Zoran
Vukovic, Nenad
Potočňák I.
Radojevic, Ivana
Čomić, Ljiljana
Trifunović, Srećko
Issue Date: 2019
Abstract: © 2018 Elsevier B.V. The five coumarin derivatives 3-(1-(2-hydroxypropylamino)ethylidene)-chroman-2,4-dione (L1), 3-(1-(phenylamino)ethylidene)-chroman-2,4-dione (L2), 3-(1-(o-toluidino)ethylidene)-chroman-2,4-dione (L3), 3-(1-(m-toluidino)ethylidene)-chroman-2,4-dione (L4), 3-(1-(2-mercaptoethylamino)ethylidene)-chroman-2,4-dione (L5) and its corresponding complexes 3-(1-(2-hydroxypropylamino)-ethylidene)-chroman-2,4-dione-palladium(II) (C1), 3-(1-(phenylamino)-ethylidene)-chroman-2,4-dione-palladium(II) (C2), 3-(1-(o-toluidino)-ethylidene)-chroman-2,4-dione-palladium(II) (C3), 3-(1-(m-toluidino)ethylidene)-chroman-2,4-dione-palladium(II) (C4), 3-(1-(2-mercaptoethylamino)ethylidene)-chroman-2,4-dione-palladium(II) (C5), were synthesized and characterized with microanalysis, infrared, 1H and 13C NMR spectroscopy. The proposed structures of ligands L3 and L4 were confirmed on the basis of the X-ray structural study. The ligands and their complexes were tested for their in vitro antimicrobial activity against 17 species of bacteria and fungi. Testing is performed by the microdilution method, with the minimum inhibitory concentration (MIC) and the minimum microbicidal concentration (MMC) being determined.
Type: article
DOI: 10.1016/j.ica.2018.09.014
ISSN: 0020-1693
SCOPUS: 2-s2.0-85053291214
Appears in Collections:Faculty of Science, Kragujevac
Institute for Information Technologies, Kragujevac

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