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Title: Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones
Authors: Pejović, Anka
Minić, Aleksandra
Bugarinović, Jovana
Pešić, Marko
Damljanović, Ivan
Stevanović, Dragana
Mihailovic, Vladimir
Katanić Stanković, Jelena S.
Bogdanovic, Goran A.
Issue Date: 2018
Abstract: © 2018 Elsevier Ltd A new series of ferrocene-containing thiazolylpyrazoles – 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones have been synthesized using convenient one-pot three component condensation. Twelve newly synthesized compounds were fully characterized by spectroscopic (IR and NMR) and electrochemical methods (cyclic voltammetry). Single crystal X-ray structure analysis were undertaken on two compounds. The twelve novel ferrocene derivatives were also evaluated for antimicrobial activity. The results showed moderate antimicrobial activity of synthesized compounds with better effect on Candida albicans and Gram-negative bacteria than Gram-positive bacterial strains.
Type: article
DOI: 10.1016/j.poly.2018.08.071
ISSN: 0277-5387
SCOPUS: 2-s2.0-85053371174
Appears in Collections:Faculty of Science, Kragujevac
Institute for Information Technologies, Kragujevac

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