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Title: Synthesis, characterization, antioxidant and antimicrobial activity of novel 5-arylidene-2-ferrocenyl-1,3-thiazolidin-4-ones
Authors: Pejović, Anka
Minić, Aleksandra
Bugarinović, Jovana
Pešić, Marko
Ilić Komatina D.
Damljanović, Ivan
Stevanović, Dragana
Mihailovic, Vladimir
Katanić Stanković, Jelena S.
Bogdanovic, Goran A.
Issue Date: 2018
Abstract: © 2018 Elsevier B.V. Synthesis of twenty novel 5-arylidene-2-ferrocenyl-1,3-thiazolidin-4-ones has been achieved in good to excellent yields by the Knoevenagel condensation of 2-ferrocenyl-1,3-thiazolidin-4-ones with aromatic aldehydes. The reaction was performed by refluxing the mixture of reactants and potassium tert-butoxide in dioxane overnight. All new compounds were characterized by the IR and NMR spectral data, and their electrochemical properties were investigated using the cyclic voltammetry. The X-ray crystal structure of one of the representative thiazolidin-4(1H)-ones is also presented. All obtained products were evaluated for their in vitro antioxidant, antibacterial and antifungal activity.
Type: article
DOI: 10.1016/j.jorganchem.2018.05.014
ISSN: 0022-328X
SCOPUS: 2-s2.0-85047253696
Appears in Collections:Faculty of Science, Kragujevac
Institute for Information Technologies, Kragujevac

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