DEVELOPMENT AND VALIDATION OF A RELIABLE LC-MS/MS METHOD FOR THE QUANTITATIVE ANALYSIS OF PESTICIDE RESIDUES IN SOIL

Abstract

In order to carry out the multi-residue determination of the pesticides in the soil the liquid chromatography coupled with tandem mass spectrometry with a triple quadrupole analyzer was applied. The basis of the method is the modified version of the environmentally friendly QuEChERS extraction. The validation parameters (linearity, recovery, precision, matrix effects, limit of detection and limit of quantification) were set in accordance with the SANTE/12682/2019. The obtained results show that the applied method represents the safe and reliable determination method for the cyprodinil, fenpropimorph, prochloraz and tebuconazole residues in the soil.