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dc.rights.licenseAttribution-ShareAlike 3.0 United States*
dc.contributor.authorMihović, Nezrina-
dc.contributor.authorMatić, Sanja-
dc.contributor.authorMladenović, Milan-
dc.contributor.authorStankovic, Nevena-
dc.contributor.authorStanić, Snežana-
dc.contributor.authorRagno, Rino-
dc.date.accessioned2023-10-26T07:22:58Z-
dc.date.available2023-10-26T07:22:58Z-
dc.date.issued2018-
dc.identifier.isbn978-86-912591-4-3en_US
dc.identifier.urihttps://scidar.kg.ac.rs/handle/123456789/19131-
dc.description.abstractThe essential oil from Ocimum basilicum L. (fam. Lamiaceae), obtained by means of steam distillation, was examined in order to determine its pharmacological potential by virtue of antimicrobial and antigenotoxic activity. Commonly called as sweet basil, considered oil is used worldwide as food flavor as well as in folk medicine for the treatment of headaches, diarrhea, coughs, constipation, warts, and kidney malfunctions; O. basilicum leaves are known for antiseptic properties as well as for the ability to destroy harmful bacteria in food; in the pharmaceutical industry, oil is used as an outstanding natural preservative. Herein, the antimicrobial activity of O. basilicum essential oil was determined according to microdilution method against six G+ and three G- bacterial strains, and one fungal species. Also, the protective effect of the essential oil on DNA damage induced by hydroxyl radical was investigated by evaluating several concentrations (25, 50, 100, 200, and 400 μg mL-1). The tested essential oil showed good antimicrobial activity according to obtained MIC values against Bacillus subtilis (1.25 μg μL-1), Bacillus cereus (0.078 μg μL-1), Enterococcus faecalis (10 μg μL-1), Staphylococcus aureus (10 μg μL-1), Staphylococcus epidermidis (2.5 μg μL-1), Micrococcus lysodeikticus (10 μg μL-1) (G+); Escherichia coli (2.5 μg μL-1), Pseudomonas aeruginosa (50 μg μL-1), Salmonella enteritidis (50 μg μL-1) (G- bacteria); Candida albicans (0.3125 μg μL-1) (fungus). DNA protective activity of essential oil was in a concentration-dependent manner and decreased with increasing concentrations. Conclusively, examined oil may be characterized as a potential therapy against infections caused by Bacillus strain as well as a supplement in cancer treatments as healthy cells protector.en_US
dc.language.isoenen_US
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rights.urihttp://creativecommons.org/licenses/by-sa/3.0/us/*
dc.source3rd International Conference of Plant Biology (22nd SPPS Meeting), Belgrade, Serbiaen_US
dc.subjectessential oil, Ocimum basilicum, antimicrobial activity, antigenotoxic potentialen_US
dc.titleAntimicrobial and antigenotoxic activity of Ocimum basilicum L. essential oilen_US
dc.typeconferenceObjecten_US
dc.description.versionAuthor's versionen_US
dc.type.versionPublishedVersionen_US
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