BENEFICIAL PROPERTIES OF TRAMETES VERSICOLOR HETEROPOLYSACCHARIDES IN A RAT MODEL OF METABOLIC SYNDROME

Abstract

We aimed to examine the potentially beneficial effects of Trametes versicolor heteropolysaccharides (TVH) on redox balance in a rats with metabolic syndrome (MetS). Total of 40 Wistar rats were divided into 5 groups: CTRL-healthy non-treated rats; MetS-non-treated rats; H-TV (high dose of TV), M-TV (medium dose of TV) and L-TV (low dose of TV)-rats with MetS treated with either 300, 200 or 100 mg/kg TVH per os for 4 weeks. Prooxidative parameters and parameters of the antioxidative defense system were determined spectrophotometrically. H-TV and M-TV significantly reduced the level of prooxidants and increased antioxidants activity. The obtained results demonstrated that the TVH may be considered a potentially useful agent for redox balance in MetS conditions.